产品货号：
Z31882
中文名称：
ENDOG抗体
英文名称：
Anti-ENDOG Antibody (Clone#7G1C10)
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ENDOG Antibody (Clone#7G1C10) |
| 指标别名 | Endo G;ENDOG;endonuclease G;Endonuclease G;mitochondrial |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | ENDOG |
| 克隆号 | 7G1C10 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Recombinant protein corresponding to amino acids 51 - 140 of human EndoG. |
| 计算分子量 | 33kDa |
| 成分 | EndoG Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | EndoG Monoclonal Antibody is Protein A purified. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | EndoG monoclonal antibody can be stored at -20℃,stable for one year. |
| 背景资料 | The fragmentation of nuclear DNA is a hallmark of apoptotic cell death.The activities of caspase and nuclease are involved in the DNA fragmentation.Caspase-activated deoxyribonuclease (CAD),also termed DNA fragmentation factor (DFF40),is one such nuclease,and is capable of inducing DNA fragmentation and chromatin condensation after cleavage by caspase-3 of its inhibitor ICAD/DFF45.Caspase and CAD independent DNA fragmentation also exists.Recent studies demonstrated that another nuclease,endonuclease G (EndoG),is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD.EndoG is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis.The homologue of mammalian EndoG is the first mitochondrial protein identified to be involved in apoptosis in C.elegans.EndoG also cleaves DNA in vitro. |
| Uniprot ID | Q14249 |
| 基因名全称 | Endonuclease G |
| 蛋白名全称 | Endonuclease G |
| 推荐稀释比 | EndoG monoclonal antibody can be used for detection of EndoG by Western blot at 2.5 ～ 5μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
相关搜索：ENDOG抗体，ENDOG单抗，Anti-ENDOG Antibody (Clone#7G1C10)